Alliance pancanadienne pharmaceutique (APP) – dernières mises à jour

État Nombre total Résumé
Négociations actives 28 Non liées à l’oncologie: 12
Liées à l’oncologie: 16
Négociations envisagées 35 Non liées à l’oncologie: 26
Liées à l’oncologie: 9
Négociations terminées 707 Avec lettre d’intention: 606
Sans entente: 101
Négociations qui n’ont pas eu lieu 104

Activités de l’APP dans les quatre dernières semaines

Marque Fabricant Indication Date d’engagement
Polivy HOFFMANN-LA ROCHE LIMITED Polatuzumab vedotin in combination with rituximab, cyclophosphamide, doxorubicin, and prednisone (R-CHP) for the treatment of adult patients with previously untreated large B-cell lymphoma (LBCL), including diffuse large B-cell lymphoma (DLBCL) not otherw
Jardiance Boehringer Ingelheim (Canada) Ltd. adjunct to standard of care therapy for the treatment of chronic heart failure in adults
Vectibix Amgen Canada Inc. In combination with chemotherapy, for the first-line treatment of mCRC patients with left-sided primary tumours that express wild-type RAS.
Jemperli GlaxoSmithKline Inc. Jemperli (dostarlimab for injection) is indicated in combination with carboplatin and paclitaxel for the treatment of adult patients with primary advanced or recurrent mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) endometrial ca
Akeega Janssen Inc. Akeega is indicated with prednisone or prednisolone for: The treatment of adult patients with deleterious or suspected deleterious BRCA mutated (germline and/or somatic) metastatic castration resistant prostate cancer (mCRPC), who are asymptomatic/mildly
Amvuttra Alnylam Netherlands B.V. Hereditary transthyretin mediated amyloidosis (hATTR amyloidosis)
Opdivo Bristol Myers Squibb Canada Inc. Cabometyx in combination with nivolumab for the first-line treatment of adult patients with advanced (not amenable to curative surgery or radiation therapy) or metastatic RCC.
Rezurock sanofi-aventis Canada Inc. For the treatment of adult and pediatric patients 12 years and older with chronic graft-versus-host disease (GVHD) after failure of at least two prior lines of systemic therapy.

Négociations achevées dans les quatre dernières semaines avec une lettre d’intention

Marque Fabricant Indication Date d’engagement Date d’achèvement
Columvi Hoffmann-La Roche Limited Glofitamab is indicated for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) not otherwise specified, DLBCL arising from follicular lymphoma (trFL), or primary mediastinal B-cell lymphoma (PMBCL), who have
Epkinly (concluded with pTAP LOI) AbbVie Corporation For the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma not otherwise specified (DLBCL NOS), DLBCL transformed from indolent lymphoma, high grade B-cell lymphoma (HGBCL), primary mediastinal B-cell lymphoma (PMBCL) or
Opdivo Bristol Myers Squibb Canada Inc. ​Opdivo, as monotherapy, is indicated for the adjuvant treatment of adult patients with Stage IIB or IIC melanoma following complete resection.
Sotyktu Bristol-Myers Squibb Company Psoriasis, moderate to severe plaque

Négociations achevées dans les quatre dernières semaines sans entente

Marque Fabricant Indication Date d’engagement Date d’achèvement
TheraSphere Y-90 Glass Micropheres Boston Scientific Corporation Hepatocellular carcinoma

Négociations que l’APP a décidé de ne pas entreprendre dans les quatre dernières semaines

Marque Fabricant Indication Aucune date de négociation
Adtralza LEO Pharma Inc. Atopic dermatitis