Alliance pharmaceutique pancanadienne (APP) – dernières mises à jour

État Nombre total Résumé
En négociation 43 Non liées à l’oncologie : 27
Liées à l’oncologie : 16
Négociations envisagées 21 Non liées à l’oncologie : 11
Liées à l’oncologie : 10
Négociations terminées 909 Avec lettre d’intention : 784
Sans entente : 125
Négociations qui n’ont pas eu lieu 113

Activités de l’APP dans les quatre dernières semaines

Marque Fabricant Indication Date d’engagement
Braftovi Pfizer Canada ULC in combination with cetuximab and chemotherapy, for the treatment of patients with metastatic colorectal cancer (mCRC) with a BRAF V600E mutation, as detected by a validated test.
Welireg Merck Canada Inc. For the treatment of adult patients with advanced renal cell carcinoma (RCC) following a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor and a vascular endothelial growth factor tyrosine kinase inhibitor (VEGF-TKI).
Qalsody Biogen Canada Inc. Amyotrophic Lateral Sclerosis (ALS)
Hepcludex Gilead Sciences Canada Inc. Chronic hepatitis delta virus (HDV) infection
Okedi Bausch Health, Canada Inc. Schizophrenia in Adults
Nemluvio Galderma Canada Inc. Prurigo nodularis
Nemluvio Galderma Canada Inc. ​For the treatment of moderate-to-severe atopic dermatitis (AD) in patients aged 12 years and older who are candidates for systemic therapy.
Enhertu AstraZeneca Canada Inc. For the treatment of adult patients with unresectable or metastatic hormone receptor (HR)-positive, HER2-low (IHC 1+ or IHC 2+/ISH-) or HER2-ultralow (IHC 0 with membrane staining) breast cancer who have received at least one endocrine therapy in the meta
Andembry CSL Behring Canada Inc. Hereditary Angioedema

Négociations achevées dans les quatre dernières semaines avec une lettre d’intention

Marque Fabricant Indication Date d’engagement Date d’achèvement
Calquence AstraZeneca Canada Inc. Indicated in combination with venetoclax for the treatment of patients with previously untreated CLL.
Calquence AstraZeneca Canada Inc. In combination with bendamustine and rituximab for the treatment of adult patients with previously untreated MCL who are ineligible for autologous stem cell transplant.
Venclexta AbbVie Corporation In combination with ibrutinib, is indicated for the treatment of adult patients with relapsed or refractory mantle cell lymphoma (MCL).
Venclexta AbbVie Corporation Calquence, in combination with venetoclex, for the treatment of patients with previously untreated chronic lymphocytic leukemia (CLL)
Imbruvica Janssen Inc. Venclexta, in combination with ibrutinib, for the treatment of adult patients with relapsed or refractory mantle cell lymphoma
Darzalex SC Janssen Inc. in combination with bortezomib, lenalidomide, and dexamethasone for the treatment of adult patients with newly diagnosed multiple myeloma who are not candidates for autologous stem cell transplant.
Columvi Hoffmann-La Roche Ltd. In combination with gemcitabine and oxaliplatin for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma not otherwise specified (DLBCL NOS) who are not candidates for autologous stem cell transplant (ASCT).
Ranvu Apotex Inc. Multiple Indications

Négociations achevées dans les quatre dernières semaines sans entente

Marque Fabricant Indication Date d’engagement Date d’achèvement
Sogroya Novo Nordisk Canada Inc. Growth hormone deficiency
Fabhalta Novartis Pharmaceuticals Canada Inc. Paroxysmal nocturnal hemoglobinuria (PNH)

Négociations que l’APP a décidé de ne pas entreprendre dans les quatre dernières semaines