pCPA Activity Overview

Status Total Negotiations Summary
Active Negotiations 50 Non-oncology: 28
Oncology: 22
Under Consideration for Negotiation 17 Non-oncology: 8
Oncology: 9
Completed Negotiations 902 With Letter of Intent: 778
Without agreement: 124
Negotiations That Were Not Pursued 113

pCPA activity in the last four weeks

Activity for the last four weeks. Please note that these updates may take one to two weeks to be processed.

Engagement letters issued in the last four weeks

Brand Name Manufacturer Indication Engagement Date
Welireg Merck Canada Inc. For the treatment of adult patients with advanced renal cell carcinoma (RCC) following a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor and a vascular endothelial growth factor tyrosine kinase inhibitor (VEGF-TKI).
Qalsody Biogen Canada Inc. Amyotrophic Lateral Sclerosis (ALS)
Hepcludex Gilead Sciences Canada Inc. Chronic hepatitis delta virus (HDV) infection
Okedi Bausch Health, Canada Inc. Schizophrenia in Adults
Nemluvio Galderma Canada Inc. Prurigo nodularis
Nemluvio Galderma Canada Inc. ​For the treatment of moderate-to-severe atopic dermatitis (AD) in patients aged 12 years and older who are candidates for systemic therapy.
Enhertu AstraZeneca Canada Inc. For the treatment of adult patients with unresectable or metastatic hormone receptor (HR)-positive, HER2-low (IHC 1+ or IHC 2+/ISH-) or HER2-ultralow (IHC 0 with membrane staining) breast cancer who have received at least one endocrine therapy in the meta
Andembry CSL Behring Canada Inc. Hereditary Angioedema
Anzupgo LEO Pharma Inc. Chronic hand eczema
Zepzelca (active pTAP negotiation) Jazz Pharmaceuticals Canada Inc. For the treatment of adult patients with Stage III or metastatic small cell lung cancer (SCLC) who have progressed on or after platinum-containing therapy.
Opzelura Incyte Biosciences Canada Corporation Atopic dermatitis

Negotiations completed in the last four weeks with a letter of intent

Brand Name Manufacturer Indication Engagement Date Close Date
Columvi Hoffmann-La Roche Ltd. In combination with gemcitabine and oxaliplatin for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma not otherwise specified (DLBCL NOS) who are not candidates for autologous stem cell transplant (ASCT).
Ranvu Apotex Inc. Multiple Indications

Negotiations completed in the last four weeks without agreement

Brand Name Manufacturer Indication Engagement Date Close Date
Fabhalta Novartis Pharmaceuticals Canada Inc. Paroxysmal nocturnal hemoglobinuria (PNH)

Negotiations that pCPA decided not to pursue in the last four weeks

Brand Name Manufacturer Indication Close Date
No negotiations that pCPA decided not to pursue in the last four weeks