pCPA Activity Overview

Status Total Negotiations Summary
Active Negotiations 36 Non-oncology: 24
Oncology: 12
Under Consideration for Negotiation 17 Non-oncology: 4
Oncology: 13
Completed Negotiations 869 With Letter of Intent: 754
Without agreement: 115
Negotiations That Were Not Pursued 112

pCPA activity in the last four weeks

Activity for the last four weeks. Please note that these updates may take one to two weeks to be processed.

Engagement letters issued in the last four weeks

Brand Name Manufacturer Indication Engagement Date
Tremfya Janssen Inc. Crohn's disease
Pombiliti with Opfolda Amicus Therapeutics Canada Inc. Pompe disease
Opdivo-Yervoy Bristol Myers Squibb Canada Inc. For the first-line treatment of adult patients with unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer.
Piasky Hoffmann-La Roche Ltd. Paroxysmal nocturnal hemoglobinuria (PNH)
Longavo Teva Canada Innovation Schizophrenia in Adults

Negotiations completed in the last four weeks with a letter of intent

Brand Name Manufacturer Indication Engagement Date Close Date
Skyrizi AbbVie Corporation Ulcerative Colitis
Repatha Amgen Canada Inc. Atherosclerotic cardiovascular disease
Winrevair Merck Canada Inc. Pulmonary Arterial Hypertension (WHO group 1)
Tagrisso AstraZeneca Canada Inc. ​For the treatment of patients with locally advanced, unresectable (stage III) non-small cell lung cancer (NSCLC) whose tumours have epidermal growth factor receptor (EGFR) exon 19 deletions or exon 21 (L858R) substitution mutations (either alone or in co
Olumiant Eli Lilly Canada Inc. Alopecia areata, severe
Camcevi Accord Healthcare Inc. For the treatment of adult patients with advanced prostate cancer

Negotiations completed in the last four weeks without agreement

Brand Name Manufacturer Indication Engagement Date Close Date
Pavblu Amgen Canada Inc. Multiple Indications
Methofill Accord Healthcare Inc. Multiple Indications

Negotiations that pCPA decided not to pursue in the last four weeks

Brand Name Manufacturer Indication Close Date
Daybue Acadia Pharmaceuticals Canada Inc. Rett syndrome