pCPA Activity Overview

Status Total Negotiations Summary
Active Negotiations 39 Non-oncology: 26
Oncology: 13
Under Consideration for Negotiation 19 Non-oncology: 7
Oncology: 12
Completed Negotiations 864 With Letter of Intent: 750
Without agreement: 114
Negotiations That Were Not Pursued 111

pCPA activity in the last four weeks

Activity for the last four weeks. Please note that these updates may take one to two weeks to be processed.

Engagement letters issued in the last four weeks

Brand Name Manufacturer Indication Engagement Date
Pombiliti with Opfolda Amicus Therapeutics Canada Inc. Pompe disease
Opdivo-Yervoy Bristol Myers Squibb Canada Inc. For the first-line treatment of adult patients with unresectable or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer.
Piasky Hoffmann-La Roche Ltd. Paroxysmal nocturnal hemoglobinuria (PNH)
Longavo Teva Canada Innovation Schizophrenia in Adults
Calquence AstraZeneca Canada Inc. In combination with bendamustine and rituximab for the treatment of adult patients with previously untreated MCL who are ineligible for autologous stem cell transplant.
Omvoh Eli Lilly Canada Inc. Crohn's disease
Penthrox Knight Therapeutics Inc. Adult patients undergoing minor gynecological, ambulatory, or emergency procedures
Nubeqa Bayer Inc. For the treatment of patients with metastatic castration-sensitive prostate cancer (mCSPC).
Vanflyta Daiichi Sankyo Pharma Canada In combination with standard cytarabineand anthracycline induction and standard cytarabine consolidationchemotherapy, and as continuation maintenance monotherapy followingconsolidation, for the treatment of adult patients with newly diagnosed acutemyeloid
Myfembree Knight Therapeutics Inc. Management of heavy menstrual bleeding associated with uterine fibroids
Stivarga Bayer Inc. For the treatment of metastatic osteosarcoma in patients who received at least 1 prior line of therapy.

Negotiations completed in the last four weeks with a letter of intent

Brand Name Manufacturer Indication Engagement Date Close Date
Olumiant Eli Lilly Canada Inc. Alopecia areata, severe
Camcevi Accord Healthcare Inc. For the treatment of adult patients with advanced prostate cancer
Opdivo SC Bristol Myers Squibb Canada Inc. Multiple Indications
Abilify Asimtufii Otsuka Canada Pharmaceutical Inc. Schizophrenia
Keytruda Merck Canada Inc. For the treatment of adult patients with FIGO 2014 Stage III-IVA cervical cancer, in combination with chemoradiotherapy (CRT).
Keytruda Merck Canada Inc. For the treatment of adult patients with resectable locally advanced head and neck squamous cell carcinoma (HNSCC) whose tumours express PD-L1 [Combined Positive Score (CPS) ≥ 1], as neoadjuvant treatment as monotherapy, continued as adjuvant treatment in
Ferinject CSL Vifor Iron deficiency in adult patients with heart failure
Ferinject CSL Vifor Iron Deficiency Anemia
Ayvakyt Medison Pharma Canada Inc. Advanced Systemic Mastocytosis

Negotiations completed in the last four weeks without agreement

Brand Name Manufacturer Indication Engagement Date Close Date
Methofill Accord Healthcare Inc. Multiple Indications
Nordimet Nordic Pharma Multiple Indications

Negotiations that pCPA decided not to pursue in the last four weeks

Brand Name Manufacturer Indication Close Date
No negotiations that pCPA decided not to pursue in the last four weeks