pCPA Activity Overview

Status Total Negotiations Summary
Active Negotiations 46 Non-oncology: 25
Oncology: 21
Under Consideration for Negotiation 22 Non-oncology: 13
Oncology: 9
Completed Negotiations 898 With Letter of Intent: 776
Without agreement: 122
Negotiations That Were Not Pursued 113

pCPA activity in the last four weeks

Activity for the last four weeks. Please note that these updates may take one to two weeks to be processed.

Engagement letters issued in the last four weeks

Brand Name Manufacturer Indication Engagement Date
Andembry CSL Behring Canada Inc. Hereditary Angioedema
Zepzelca (active pTAP negotiation) Jazz Pharmaceuticals Canada Inc. For the treatment of adult patients with Stage III or metastatic small cell lung cancer (SCLC) who have progressed on or after platinum-containing therapy.
Anzupgo LEO Pharma Inc. Chronic hand eczema
Opzelura Incyte Biosciences Canada Corporation Atopic dermatitis
Sarclisa Sanofi Genzyme Canada In combination with bortezomib, lenalidomide, and dexamethasone, for the treatment of patients with newly diagnosed multiple myeloma who are not eligible for autologous stem cell transplant (ASCT).
Itovebi Hoffmann-La Roche Ltd. In combination with palbociclib and fulvestrant for the treatment of adult patients with endocrine resistant, PIK3CA-mutated, hormone receptor-positive (HR+) (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or meta
Epuris Cipher Acne Vulgaris
Quviviq Idorsia Pharmaceuticals Canada Ltd. Insomnia
Rebyota Ferring Canada Inc. Clostridioides difficile infection, prevention
Perjeta Hoffmann-La Roche Ltd. In combination with trastuzumab and chemotherapy for the neoadjuvant treatment of adult patients with early-stage HER2-positive breast cancer
Alyftrek Vertex Pharmaceuticals (Canada) Incorporated Cystic fibrosis, F508del or responsive CFTR mutation, 6 years and older
Lyvdelzi Gilead Sciences Canada Inc. For the treatment of primary biliary cholangitis (PBC), in combination with ursodeoxycholic acid (UDCA) in adults who have an inadequate response to UDCA alone, or as monotherapy in adults unable to tolerate UDCA.
Ranvu Apotex Inc. Multiple Indications

Negotiations completed in the last four weeks with a letter of intent

Brand Name Manufacturer Indication Engagement Date Close Date
Voranigo Servier Canada Inc. For the treatment of Grade 2 WHO 2016, 2021 grading system astrocytoma or oligodendroglioma with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation or isocitrate dehydrogenase-2 (IDH2) mutation in adults and pediatric patients aged 12 years and olde
Mavenclad EMD Serono Canada, a division of EMD Inc. Multiple Sclerosis, Relapsing-Remitting

Negotiations completed in the last four weeks without agreement

Brand Name Manufacturer Indication Engagement Date Close Date
No negotiations completed without agreement in the last four weeks

Negotiations that pCPA decided not to pursue in the last four weeks

Brand Name Manufacturer Indication Close Date
No negotiations that pCPA decided not to pursue in the last four weeks