Alliance pharmaceutique pancanadienne (APP) – dernières mises à jour

État Nombre total Résumé
En négociation 45 Non liées à l’oncologie : 24
Liées à l’oncologie : 21
Négociations envisagées 20 Non liées à l’oncologie : 11
Liées à l’oncologie : 9
Négociations terminées 898 Avec lettre d’intention : 776
Sans entente : 122
Négociations qui n’ont pas eu lieu 113

Activités de l’APP dans les quatre dernières semaines

Marque Fabricant Indication Date d’engagement
Zepzelca (active pTAP negotiation) Jazz Pharmaceuticals Canada Inc. For the treatment of adult patients with Stage III or metastatic small cell lung cancer (SCLC) who have progressed on or after platinum-containing therapy.
Opzelura Incyte Biosciences Canada Corporation Atopic dermatitis
Anzupgo LEO Pharma Inc. Chronic hand eczema
Sarclisa Sanofi Genzyme Canada In combination with bortezomib, lenalidomide, and dexamethasone, for the treatment of patients with newly diagnosed multiple myeloma who are not eligible for autologous stem cell transplant (ASCT).
Epuris Cipher Acne Vulgaris
Itovebi Hoffmann-La Roche Ltd. In combination with palbociclib and fulvestrant for the treatment of adult patients with endocrine resistant, PIK3CA-mutated, hormone receptor-positive (HR+) (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, locally advanced or meta
Perjeta Hoffmann-La Roche Ltd. In combination with trastuzumab and chemotherapy for the neoadjuvant treatment of adult patients with early-stage HER2-positive breast cancer
Rebyota Ferring Canada Inc. Clostridioides difficile infection, prevention
Alyftrek Vertex Pharmaceuticals (Canada) Incorporated Cystic fibrosis, F508del or responsive CFTR mutation, 6 years and older
Lyvdelzi Gilead Sciences Canada Inc. For the treatment of primary biliary cholangitis (PBC), in combination with ursodeoxycholic acid (UDCA) in adults who have an inadequate response to UDCA alone, or as monotherapy in adults unable to tolerate UDCA.
Quviviq Idorsia Pharmaceuticals Canada Ltd. Insomnia
Ranvu Apotex Inc. Multiple Indications
Carvykti Janssen Inc. (du) Multiple myeloma in adult patients who have received at least three prior therapies, including an immunomodulatory agent, a proteasome inhibitor, and an anti-CD38 antibody and who are refractory to their last treatment
Carvykti Janssen Inc. For the treatment of adult patients with multiple myeloma, who have received 1 to 3 prior lines of therapy including a proteasome inhibitor and an immunomodulatory agent, and who are refractory to lenalidomide.
Calquence AstraZeneca Canada Inc. Indicated in combination with venetoclax for the treatment of patients with previously untreated CLL.
Venclexta AbbVie Corporation Calquence, in combination with venetoclex, for the treatment of patients with previously untreated chronic lymphocytic leukemia (CLL)

Négociations achevées dans les quatre dernières semaines avec une lettre d’intention

Marque Fabricant Indication Date d’engagement Date d’achèvement
Voranigo Servier Canada Inc. For the treatment of Grade 2 WHO 2016, 2021 grading system astrocytoma or oligodendroglioma with a susceptible isocitrate dehydrogenase-1 (IDH1) mutation or isocitrate dehydrogenase-2 (IDH2) mutation in adults and pediatric patients aged 12 years and olde
Mavenclad EMD Serono Canada, a division of EMD Inc. Multiple Sclerosis, Relapsing-Remitting
Opdivo-Yervoy Bristol Myers Squibb Canada Inc. For the first-line treatment of adult patients with unresectable or advanced hepatocellular carcinoma (HCC).

Négociations achevées dans les quatre dernières semaines sans entente

Marque Fabricant Indication Date d’engagement Date d’achèvement
Ofev Boehringer Ingelheim (Canada) Ltd. Idiopathic pulmonary fibrosis and PF-ILD
Spevigo Boehringer Ingelheim (Canada) Ltd. generalized pustular psoriasis (GPP)

Négociations que l’APP a décidé de ne pas entreprendre dans les quatre dernières semaines